Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...

(CNN) — Each human is a finely tuned orchestra of more than 37 trillion cells. Mapping this little-known world is one of biology’s greatest challenges — and one in which scientists say they just made ...

Researchers have created an early map of some of the human body’s estimated 37.2 trillion cells. Each type of cell has a unique role, and knowing what all the cells do can help scientists better ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

A sac-like structure formed by day 10 in over 90% of the PGAs. These gradually expanded in size over 90 days, without being given any further signals. The cell composition in the models showed ...