During development of chordates, establishment of the body plan relies on the activity of an organizing centre located on the dorsal side of the embryo that patterns the embryo and induces neural ...

These papers were the first steps of a formidable challenge: understanding how the Spemann organizer builds the vertebrate body. “What should I read?” is the classic question I receive from new ...

Cells need to 'know' where they are in relation to all other cells in order to give rise into the correct cell types and tissues. The so-called 'organizer' is responsible for the formation of these ...