The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...
Waters WAT recently unveiled its Alliance iS Bio high-performance liquid chromatography (HPLC) system, designed to improve efficiency by saving time and reducing errors. The instrument uses Waters ...
Challenging method conditions can impact autosampler performance on High-Performance Liquid Chromatography (HPLC) systems. Methods with highly organic sample diluents, coupled with low injection ...
Leveraging the full potential of FcRn-pH-HPLC enables Affimed an early selection of innate cell engagers (ICE ®) with tailored pharmacokinetic (PK) profiles and to thereby develop drug candidates with ...
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