On a daily basis, multitudes of molecules enter each cell in our body. These can be nutrients or signal molecules or pathogenic microorganisms. An organelle in the cell directs these molecules to ...

A recent study by a group of scientists from Japan and Austria has revealed that a different mechanism is responsible for the formation and maintenance of the cell organelle called endosome that sorts ...

The general amino acids permease Gap1p provides yeast with sufficient amino acids to maintain protein synthesis. Gap1p is translocated to the plasma membrane when amino acids become limiting, a ...

Delivery of transmembrane proteins to the lumen of the lysosome is mediated by their ubiquitination, and subsequent recognition and sorting at the endosome. A new group of ubiquitin-binding proteins ...

A recent study by a group of scientists has revealed that a different mechanism is responsible for the formation and maintenance of the cell organelle called endosome that sorts and distributes ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University of Connecticut researchers have shown that packaging mRNA like a virus could ...

Researchers shamelessly copy viral strategies to get mRNA medicines into cells in one piece (Illustration courtesy of Joe Luciani ...