Like a beloved pair of jeans, human DNA accumulates damage over time, and older people's bodies can't repair it as well. Many scientists believe a build up of damage can cause cells to enter an ...

A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In this ...

This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...

“Our work highlights the need to study polyploidy and senescence in concert to understand their roles in aging, cancer, and therapeutic resistance.” “Our work highlights the need to study polyploidy ...

The key to reversing cellular aging may lie in a protein responsible for toggling cells between a "young" and an "old" state. This is the conclusion of researchers from the University of Osaka, who ...

A new research paper was published in Volume 18 of Aging-US on February 10, 2026, titled “Aging-associated mitochondrial circular RNAs.” Led by first author Hyejin Mun from the University of Oklahoma ...

Growing old isn’t always fun, but research suggests it may ward off cancer. In A Nutshell While cancer risk climbs through most of life, it actually levels off and can decline in people over 85, a ...