To explore the clinical value of noninvasive prenatal testing (NIPT) combined with chromosomal microarray analysis (CMA)/copy number variation sequencing (CNV-seq), methylation-specific multiplex ...

Sex chromosome abnormalities (SCAs), also known as X or Y chromosome abnormalities, can lead to dysplasia of sexual organs in both males and females 1. SCAs are relatively common, with an estimated ...

Using this method, they found that a combination of failures—from the partial loss of an essential protein to weakened connections between chromosomes—can cause errors that increase with maternal age.

When couples have trouble conceiving a baby or lose a pregnancy, they often undergo routine tests, which can turn up a shock: One of the prospective parents may be missing a chromosome. The most ...

Sex chromosomes are chromosomes, or packages of DNA, that are found inside the nucleus of all of your cells. There are two different kinds: X and Y, which determine whether you’re biologically male ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...