Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

Osteoarthritis (OA) is the most common form of degenerative joint disease in the world, affecting more than 27 million people in the US and costing nearly over two hundred billion dollars annually.

The articular cartilage and meniscus in the knee joint are critical for painless movement, but these tissues’ have low regeneration capacities, rendering them vulnerable to injury and osteoarthritis ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Researchers showed that extracellular vesicles from menstrual cells stimulate cartilage repair. The new approach offers a ...

αKG induces a relatively reductive state within chondrocytes, promotes the extracellular lactate shuttle into the cells and H3K56 lactylation modification, and positively regulates the expression of ...

Knee cartilage usually wears down quietly. Over time, that loss can turn walking stairs into a daily calculation. Now a Stanford Medicine-led team reports that blocking a single age-linked protein ...

In patients with severe osteoarthritis, cartilage can wear so thin that joints essentially transform into bone on bone — without a cushion between. A new therapy that uses synthetic nanofibers to ...

Even though the recently launched EU project ENCANTO (“magic” in Spanish) has nothing to do with the Disney movie of the same name, the study topic might sound like magic to the layman. "We take a ...