Investigators at CHOP and UPenn found that lower cell counts could still be associated with poor outcomes if the cells were ...

For years, researchers have been trying to figure out how to treat inherited blood disorders like sickle cell disease without causing new health problems in the process. Now, a team of scientists from ...

A new CRISPR-based tool that is directly used on patients' cancer cells can identify genes and regulatory elements driving ...

This article and associated images are based on a poster originally authored by Donato Tedesco, Tianbing Liu, Dongfang Hu, Nadya Isachenko, Debbie Deng, Paul Diehl and Alex Chenchik and presented at ...

Gene editing has moved from theory to bedside with a speed that would have seemed impossible a decade ago. A new wave of CRISPR advances is not only correcting single mutations in the lab but ...

Although existing CRISPR-Cas-based imaging methods can target endogenous genomic sequences, their applications are limited by system complexity and sensitivity, particularly when imaging ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, ...

A new light-based sensor detects cancer markers at near-zero concentrations.

A novel CRISPR-based technology can spread within bacterial populations to eliminate antibiotic resistance. In a potential breakthrough for tackling antibiotic resistance, researchers from the ...